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Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells.
Scientific Reports. 2018 8:2206 DOI:10.1038/s41598-018-20360-x
hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage.
Oncotarget. 2017 dx.doi.org/10.18632/oncotarget.21619
Analysis of CTCL cell lines reveals important differences between mycosis fungoides/Sézary syndrome vs. HTLV-1+ leukemic cell lines.
BMC Molecular Biology. 2017 Jul 20;18(1):19. doi: 10.1186/s12867-017-0096-x
Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA.
Nature Communications. 2017 May 31;8:15615. doi: 10.1038/ncomms15615
R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.
PLoS One. 2017 May 11;12(5):e0176880. doi: 10.1371/journal.pone.0176880
Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virus-associated gastric carcinomas.
OncoImmunology. 2017 dx.doi.org/10.1080/2162402X.2017.1306618
Gene expression analysis in Cutaneous T-Cell Lymphomas (CTCL) highlights disease heterogeneity and potential diagnostic and prognostic indicators.
Cell Reports. 2016 17(8), 1990 DOI 10.1016/j.celrep.2016.10.071
SRSF10 Connects DNA Damage to the Alternative Splicing of Transcripts Encoding Apoptosis, Cell-Cycle Control, and DNA Repair Factors.
BMC Genomics. 2016 17(1), 683 DOI 10.1186/s12864-016-3029-z
Global profiling of alternative RNA splicing events provides insights into molecular differences between various types ofhepatocellular carcinoma.
PLoS One. 2016 Sep 6;11(9):e0161914. doi: 10.1371/journal.pone.0161914
Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions.
Scientific Reports. 2015 Sep 22;5:14301. doi: 10.1038/srep14301
Tumor-promoting role of SOCS1 in colorectal cancer cells.
PLoS One. 2015 May 19;10(5):e0125998. doi: 10.1371/journal.pone.0125998
Neural differentiation modulates the vertebrate brain specific splicing program.
PLoS One. 2014 Sep 11;9(9):e107324. doi: 10.1371/journal.pone.0107324
RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1.
BMC Medical Genetics. 2014 Aug 14;15:98. doi: 10.1186/s12881-014-0098-1
Alternative splicing in osteoclasts and Paget's disease of bone.
Nucleic Acids Research. 2014 Apr;42(6):e40. doi: 10.1093/nar/gkt1287
Redirecting splicing with bifunctional oligonucleotides.
RNA. 2014 Feb;20(2):189-201. doi: 10.1261/rna.042168.113
Tumor microenvironment-associated modifications of alternative splicing.
Nature Communications. 2013 4:2480. doi: 10.1038/ncomms3480
MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation.
Molecular and Cellular Biology. 2013 Jan;33(2):396-405. doi: 10.1128/MCB.01174-12
RBFOX2 is an important regulator of mesenchymal tissue-specific splicing in both normal and cancer tissues.
Molecular and Cellular Biology. 2012 Mar;32(5):954-67. doi: 10.1128/MCB.06130-11
Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.
Nature Structural & Molecular Biology. 2011 Jun;18(6):673-9. doi: 10.1038/nsmb.2040
Alternative splicing of SYK regulates mitosis and cell survival.
Human Molecular Genetics. 2011 Jun 1;20(11):2116-30. doi: 10.1093/hmg/ddr094
PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.
RNA. 2010 Feb;16(2):442-9. doi: 10.1261/rna.1877010
High-throughput quantification of splicing isoforms.
Nature Structural & Molecular Biology. 2009 Jun;16(6):670-6. doi: 10.1038/nsmb.1608
Cancer-associated regulation of alternative splicing.
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Identification of alternative splicing markers for breast cancer.
Molecular and Cellular Biology. 2008 Oct;28(19):6033-43. doi: 10.1128/MCB.00726-08
Multiple and specific mRNA processing targets for the major human hnRNP proteins.
Cancer Research. 2008 Feb 1;68(3):657-63. doi: 10.1158/0008-5472.CAN-07-2580
Multiple alternative splicing markers for ovarian cancer.