OncoImmunology. 2017 dx.doi.org/10.1080/2162402X.2017.1306618

Gene expression analysis in Cutaneous T-Cell Lymphomas (CTCL) highlights disease heterogeneity and potential diagnostic and prognostic indicators.

Litvinov IV, Tetzlaff MT, Thibault P, Gangar P, Moreau L, Watters AK, Netchiporouk E, Prieto VG, Rahme E, Sasseville D, Duvic M.


Cell Reports. 2016 17(8), 1990 DOI 10.1016/j.celrep.2016.10.071

SRSF10 Connects DNA Damage to the Alternative Splicing of Transcripts Encoding Apoptosis, Cell-Cycle Control, and DNA Repair Factors.

Shkreta L, Toutant J, Durand M, Manley JL, Chabot B.


Nat Commun. 2016 submitted reference number: NCOMMS-16-19992

The RUVBL1/RUVBL2 component of the cochaperone R2TP/Prefoldin-like directly interacts with ZNHIT2 to regulate assembly of the U5 small nuclear ribonucleoprotein.

Cloutier P, Poitras C, Durand M, Fiola-Masson E, Bouchard A, Faubert D, Chabot B, Coulombe B.


BMC Cancer. 2016 submitted reference number: BCAN-D-16-00954

Global profiling of alternative RNA splicing events in gastric cancer highlights a novel role for the Epstein-Barr virus EBNA1 protein.

Armero VES, Tremblay MP, Allaire A, Boudreault S, Duval C; Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Bisaillon M.


BMC Genomics. 2016 17(1), 683 DOI 10.1186/s12864-016-3029-z

Global profiling of alternative RNA splicing events provides insights into molecular differences between various types ofhepatocellular carcinoma.

Tremblay MP, Armero VES, Allaire A, Boudreault S, Martenon-Brodeur C, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Bisaillon M.


PLoS One. 2016 Sep 6;11(9):e0161914. doi: 10.1371/journal.pone.0161914

Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions.

Boudreault S, Martenon-Brodeur C, Caron M, Garant JM, Tremblay MP, Armero VE, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Lemay G, Bisaillon M.


Sci Rep. 2015 Sep 22;5:14301. doi: 10.1038/srep14301

Tumor-promoting role of SOCS1 in colorectal cancer cells.

Tobelaim WS, Beaurivage C, Champagne A, Pomerleau V, Simoneau A, Chababi W, Yeganeh M, Thibault P, Klinck R, Carrier JC, Ferbeyre G, Ilangumaran S, Saucier C.


PLoS One. 2015 May 19;10(5):e0125998. doi: 10.1371/journal.pone.0125998

Neural differentiation modulates the vertebrate brain specific splicing program.

Madgwick A, Fort P, Hanson PS, Thibault P, Gaudreau MC, Lutfalla G, Möröy T, Abou Elela S, Chaudhry B, Elliott DJ, Morris CM, Venables JP.


PLoS One. 2014 Sep 11;9(9):e107324. doi: 10.1371/journal.pone.0107324

RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1.

Klinck R, Fourrier A, Thibault P, Toutant J, Durand M, Lapointe E, Caillet-Boudin ML, Sergeant N, Gourdon G, Meola G, Furling D, Puymirat J, Chabot B.


BMC Med Genet. 2014 Aug 14;15:98. doi: 10.1186/s12881-014-0098-1

Alternative splicing in osteoclasts and Paget's disease of bone.

Klinck R, Laberge G, Bisson M, McManus S, Michou L, Brown JP, Roux S.


Nucleic Acids Res. 2014 Apr;42(6):e40. doi: 10.1093/nar/gkt1287

Redirecting splicing with bifunctional oligonucleotides.

Brosseau JP, Lucier JF, Lamarche AA, Shkreta L, Gendron D, Lapointe E, Thibault P, Paquet E, Perreault JP, Abou Elela S, Chabot B.


RNA. 2014 Feb;20(2):189-201. doi: 10.1261/rna.042168.113

Tumor microenvironment-associated modifications of alternative splicing.

Brosseau JP, Lucier JF, Nwilati H, Thibault P, Garneau D, Gendron D, Durand M, Couture S, Lapointe E, Prinos P, Klinck R, Perreault JP, Chabot B, Abou-Elela S.


Nat Commun. 2013 4:2480. doi: 10.1038/ncomms3480

MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation.

Venables JP, Lapasset L, Gadea G, Fort P, Klinck R, Irimia M, Vignal E, Thibault P, Prinos P, Chabot B, Abou Elela S, Roux P, Lemaitre JM, Tazi J.


Mol Cell Biol. 2013 Jan;33(2):396-405. doi: 10.1128/MCB.01174-12

RBFOX2 is an important regulator of mesenchymal tissue-specific splicing in both normal and cancer tissues.

Venables JP, Brosseau JP, Gadea G, Klinck R, Prinos P, Beaulieu JF, Lapointe E, Durand M, Thibault P, Tremblay K, Rousset F, Tazi J, Abou Elela S, Chabot B.


Mol Cell Biol. 2012 Mar;32(5):954-67. doi: 10.1128/MCB.06130-11

Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.

Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R, Elela SA, Prinos P, Chabot B.


Nat Struct Mol Biol. 2011 Jun;18(6):673-9. doi: 10.1038/nsmb.2040

Alternative splicing of SYK regulates mitosis and cell survival.

Prinos P, Garneau D, Lucier JF, Gendron D, Couture S, Boivin M, Brosseau JP, Lapointe E, Thibault P, Durand M, Tremblay K, Gervais-Bird J, Nwilati H, Klinck R, Chabot B, Perreault JP, Wellinger RJ, Abou Elela S.


Hum Mol Genet. 2011 Jun 1;20(11):2116-30. doi: 10.1093/hmg/ddr094

PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.

Tanackovic G, Ransijn A, Thibault P, Abou Elela S, Klinck R, Berson EL, Chabot B, Rivolta C.


RNA. 2010 Feb;16(2):442-9. doi: 10.1261/rna.1877010

High-throughput quantification of splicing isoforms.

Brosseau JP, Lucier JF, Lapointe E, Durand M, Gendron D, Gervais-Bird J, Tremblay K, Perreault JP, Abou Elela S.


Nat Struct Mol Biol. 2009 Jun;16(6):670-6. doi: 10.1038/nsmb.1608

Cancer-associated regulation of alternative splicing.Cancer-associated regulation of alternative splicing.

Venables JP, Klinck R, Koh C, Gervais-Bird J, Bramard A, Inkel L, Durand M, Couture S, Froehlich U, Lapointe E, Lucier JF, Thibault P, Rancourt C, Tremblay K, Prinos P, Chabot B, Abou Elela S.


Cancer Res. 2008 Nov 15;68(22):9525-31. doi: 10.1158/0008-5472.CAN-08-1769

Identification of alternative splicing markers for breast cancer.

Venables JP, Klinck R, Bramard A, Inkel L, Dufresne-Martin G, Koh C, Gervais-Bird J, Lapointe E, Froehlich U, Durand M, Gendron D, Brosseau JP, Thibault P, Lucier JF, Tremblay K, Prinos P, Wellinger RJ, Chabot B, Rancourt C, Abou Elela S.


Mol Cell Biol. 2008 Oct;28(19):6033-43. doi: 10.1128/MCB.00726-08

Multiple and specific mRNA processing targets for the major human hnRNP proteins.

Venables JP, Koh CS, Froehlich U, Lapointe E, Couture S, Inkel L, Bramard A, Paquet ER, Watier V, Durand M, Lucier JF, Gervais-Bird J, Tremblay K, Prinos P, Klinck R, Abou Elela S, Chabot B.


Cancer Res. 2008 Feb 1;68(3):657-63. doi: 10.1158/0008-5472.CAN-07-2580

Multiple alternative splicing markers for ovarian cancer.

Klinck R, Bramard A, Inkel L, Dufresne-Martin G, Gervais-Bird J, Madden R, Paquet ER, Koh C, Venables JP, Prinos P, Jilaveanu-Pelmus M, Wellinger R, Rancourt C, Chabot B, Abou Elela S.